Academic Medicinal Chemistry PCI 2026 (NEP 2020) Paid Access

Medicinal Chemistry (Practical)

By Prof. Ashish Ramesh Jadhav & Prof. Shounak Rajendra Mande

This laboratory text has been written for the course BP407P Medicinal Chemistry (Practical) of the fourth semester of the Bachelor of Pharmacy programme. It follows the prescribed syllabus experiment by experiment and covers all fifteen experiments listed, so that each institution may select any three assays and any three monographs in addition to the six preparations.
Category
Pharmaceutical Chemistry
Target Audience
B.Pharm IV Semester Students
Course Code
BP407P
Syllabus
New PCI 2026 (NEP 2020)
ISBN
978-81-181871-1-0
Experiments
15 Experiments (6 Preparations, 4 Assays, 5 Monographs)

About This Book

Each experiment is presented in the order in which it is performed and recorded: aim, principle with reaction scheme and mechanism, requirements, procedure, flow chart, observation table, calculation, result, precautions, uses and viva-voce questions. Observation tables carry the layout, units and one specimen entry; the remaining rows are left for the student to complete at the bench.

All molar masses, theoretical yields and equivalence factors have been recalculated, and the pharmacopoeial specifications quoted follow the Indian Pharmacopoeia. Where a later edition revises a limit, the current edition of the IP prevails.

Chapter 1 sets out the common laboratory operations once, so that the experiments that follow refer to them rather than repeating them. The appendices collect the preparation and standardisation of volumetric solutions, the indicators and the reagent solutions.

List of Experiments

Chapter 1 — Fundamentals of the Medicinal Chemistry Laboratory (scope, laboratory safety, glassware and apparatus, unit operations in synthesis, characterisation of the product, calculation of yield, principles of titrimetric assay, weighing and titration technique, writing the practical record, viva voce)

Preparation of Drugs and Intermediates

  1. Preparation of Aspirin (Acetylsalicylic Acid)
  2. Preparation of Benzotriazole
  3. Preparation of Benzocaine (Ethyl p-Aminobenzoate)
  4. Preparation of Phenytoin (5,5-Diphenylhydantoin)
  5. Preparation of Dibenzalacetone (Dibenzylideneacetone)
  6. Preparation of Paracetamol (4-Hydroxyacetanilide)

Assay of Drugs

  1. Assay of Aspirin
  2. Assay of Ibuprofen
  3. Assay of Furosemide
  4. Assay of Paracetamol

Monograph Analysis

  1. Monograph Analysis of Paracetamol
  2. Monograph Analysis of Aspirin
  3. Monograph Analysis of Phenobarbital
  4. Monograph Analysis of Diclofenac Sodium
  5. Monograph Analysis of Phenytoin

Appendices: A — Preparation and Standardisation of Volumetric Solutions; B — Indicators and Reagents; C — Model Questions for the Practical Examination; D — Glossary of Terms; E — Recommended References.

Keywords

Medicinal Chemistry Practical Drug Synthesis Aspirin Benzotriazole Benzocaine Phenytoin Dibenzalacetone Paracetamol Assay of Drugs Monograph Analysis Indian Pharmacopoeia Titrimetric Assay Recrystallisation Reflux Melting Point B.Pharm BP407P PCI Syllabus 2026 NEP 2020

How to Cite

Jadhav, A. R., & Mande, S. R. (2026). Medicinal Chemistry (Practical) (1st ed.). WiseLeaf Scientific Ventures. ISBN: 978-81-181871-1-0

DOI: 10.66079/wiseleaf.medicinal-chemistry-practical-bp407p.2026

Paid Access — Preview the first 10 pages for free. Full book will be available for purchase through our partner platforms.

Back to Books Catalog

Related WiseLeaf titles